Aiming at the problem of energy hole in the nodes non-uniform deployment network model based on the ring in Wireless Sensor Network (WSN), a Ring-based Clustering Algorithm for Nodes Non-uniform Deployment (RCANND) was proposed. The number of the optimal cluster heads in each ring was calculated by minimizing the energy consumption of each ring in the nodes non-uniform deployment network model. The cluster head selectivity was calculated by using the residual energy of the nodes, the distance from the base station, and the average distance from the neighbor nodes. The cluster head rotation was carried out with the cluster head selection sequence in cluster, and the number of cluster formation phases was reduced to improve the efficiency of network energy utilization. The proposed algorithm was tested in the simulation experiments, the experimental results show that, the average energy consumption fluctuation of nodes under the same radius but different nodes deployment models is very small. The average energy consumption fluctuation of nodes under the same nodes deployment model but different radiuses is not obvious. The network lifetime was defined as the survivability of 50% network nodes. In the case of non-uniform deployment of nodes, the network lifetime of the proposed algorithm is higher than that of Unequal Hybrid Energy Efficient Distributed algorithm (UHEED) by about 18.1% while it is also higher than that of Rotated Unequal Hybrid Energy Efficient Distributed algorithm (RUHEED) by about 11.5%. In the case of uniform deployment of nodes, the network lifetime of the proposed algorithm is higher than that of sub-Ring-based Energy-efficient Clustering Routing for WSN (RECR) by about 6.4%. The proposed algorithm can effectively balance the energy consumption under different nodes deployment models and prolong the network lifetime.